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Short Answer Questions · Q26

Q.State the significance of testosterone and of estrogen as gonadal hormones, naming the cells/tissue that secrete each.

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Testosterone, secreted by the interstitial cells of Leydig in the testis under LH stimulation, is responsible for the development of the male reproductive organs during fetal life, the appearance of male secondary sexual characters at puberty (facial/body hair, deepened voice, increased muscle mass), and, together with FSH acting on the Sertoli cells, for the ongoing maintenance of spermatogenesis. Estrogen, secreted chiefly by the cells surrounding the developing Graafian follicle under FSH stimulation, is responsible for development of the female reproductive organs during fetal life, the appearance of female secondary sexual characters at puberty (breast development, pelvic broadening), and for stimulating prolifera …

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