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Short Answer Questions · Q27

Q.Distinguish between negative feedback and positive feedback control of hormone secretion, giving one example of each from the endocrine system.

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In negative feedback, the dominant pattern across the endocrine system, a rising level of the hormone produced at the end of a control chain acts back on the gland(s) that stimulated its release, damping down further stimulation -- for example, rising T3/T4 act back on the hypothalamus and anterior pituitary to suppress further TRH and TSH release, preventing thyroid hormone level from climbing unchecked. In positive feedback, a much rarer pattern, a rising hormone level instead drives still more of the same response -- as in oxytocin release during childbirth, where uterine stretch triggers oxytocin release, which intensifies contraction, further increasing stret …

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