Individual atoms are far too light to be weighed directly on a laboratory balance, so chemists express atomic
mass on a relative scale rather than in grams. One atomic mass unit (u) is defined as exactly 121 of
the mass of a single atom of the carbon-12 isotope, so 1 u≈1.66×10−24 g. On
this scale, hydrogen has an atomic mass of about 1.008 u and oxygen about 16.00 u.
Most elements occur in nature as a fixed mixture of two or more isotopes — atoms with the same number of
protons but different numbers of neutrons, and hence slightly different masses. The atomic mass listed for an
element on the periodic table is therefore not the mass of any single atom, but the abundance-weighted average
across all of that element's naturally occurring isotopes:
Average atomic mass=∑(fractional abundance)×(isotopic mass)
Chlorine, for example, occurs as roughly 76% 35Cl and 24% 37Cl, giving a weighted
average atomic mass of about 35.45 u — a value that is not itself the mass of either isotope.
The molecular mass of a substance is the sum of the atomic masses of every atom present in one molecule of
that substance, with each atomic mass multiplied by the number of times that element appears in the molecular
formula. For water, H2O, the molecular mass is 2(1.008)+16.00=18.02 u. …