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Long Answer Questions · Q34

Q.Describe the structure, formation and functions of the human placenta.

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After implantation, the trophoblast develops numerous finger-like chorionic villi that grow into the surrounding endometrium; as pregnancy advances these villi become richly supplied with foetal blood vessels (connected to the foetus via the umbilical cord, carrying two umbilical arteries and one umbilical vein) and are bathed on their outer surface in pools of maternal blood, together forming the placenta. Maternal and foetal blood do not normally mix directly; exchange occurs by diffusion and active transport across the villus walls. Functionally, the placenta supplies the foetus with glucose, amino acids, fatty acids, vitamins and minerals from maternal blood; carries out respiratory gas exchange, allowing oxygen to pass to the foetus and carbon dioxide to pass to the mother, acting as the foetus's lungs before birth; removes foetal nitrogenous wastes into the maternal circulation for excretion; and acts as a selective (though incomplete) barrier, allowing maternal antibodies and some drugs/pathogens to cross while excluding others. Beyond exchange, the placenta is also a temporary endocrine gland: it secretes hCG, which in early pregnancy maintains the maternal corpus luteum's progesterone output; human placental lactogen, which alters maternal …

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