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Question 39 of 49

Q.(i) Deficiency of which vitamin causes pernicious anaemia?

(ii) Between sucrose and maltose, which is a reducing sugar?
(iii) Write with chemical equation what happens when D-glucose is treated with bromine water. (1+1+1)
West Bengal WbchseWest Bengal HS (WBCHSE) Board 2023Subjective· 3mImportance★★★★★
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B12 deficiency causes pernicious anaemia; maltose has a free anomeric -OH so it reduces Fehling's/Tollens' reagent, sucrose does not; bromine water mildly oxidises glucose's aldehyde group.

  1. A deficiency of Vitamin B12 (cobalamin) impairs red blood cell maturation and causes pernicious anaemia.
  2. Maltose is formed from two glucose units joined by an alpha-1,4-glycosidic bond, leaving one anomeric carbon free with its -OH group intact (a potential aldehyde/hemiacetal); this free reducing end lets maltose reduce Fehling's and Tollens' reagents, making it a reducing sugar. Sucrose, by contrast, is formed by a glycosidic bond between the anomeric carbons of BOTH glucose and fructose, leaving no free anomeric -OH — it cannot reduce Fehling's/Tollens' reagent and is a non-reducing sugar. …

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