Q.-D(+) Glucose and -D(+) Glucose are :
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Start your 14-day free trial to unlock the full solution →When glucose cyclises to its ring (pyranose/furanose) form, a new stereocentre is created at C-1; the two possible configurations at just this one carbon give rise to - and -D-glucose, a relationship specifically called anomerism.
When the open-chain form of D-glucose cyclises (the at C-5 attacking the aldehyde carbon, C-1), a new asymmetric (stereogenic) carbon is created at C-1, called the anomeric carbon. Depending on the spatial orientation of the newly formed group at this carbon (relative to the reference group at C-5), two distinct cyclic forms result: -D(+)-glucose (with the C-1 on the opposite side to the reference group) and -D(+)-glucose (same side). Since these two forms differ in configuration at only this one carbon (the anomeric carbon) while all other stereocentres remain identical, they are called anomers — a special sub-class of diastereomers (epimers differ at any single stereocentre in general, b …
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