Q.Give any two bioactive molecules produced by microbes and state their uses.
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Start your 14-day free trial to unlock the full solution →Cyclosporin A and statins are two well-known bioactive molecules of microbial origin, used respectively as an immunosuppressant and a cholesterol-lowering drug.
Micro-organisms are an important commercial source of bioactive molecules used in medicine. Cyclosporin A is produced by the fungus Trichoderma polysporum; it suppresses the immune system's rejection response and is administered to organ-transplant patients to prevent their body from rejecting the transplanted organ. Statins are produced by the yeast Monascus purpureus; they act by competitively inhibiting the enzyme HMG-CoA reductase, which is central to cholesterol biosynthesis in the liver, and so are used clinically to lower blood cholesterol levels and reduce the risk of cardiovascular disease. (Other examples taught alongside these include streptokinase, from Streptococcus and modified by genetic …
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