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NCERT Exemplar · Q30

Q.It is known that red muscle fibres in animals can work for longer periods of time continuously. How is this possible?

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Red muscle fibres sustain long, continuous activity because their abundant myoglobin and high mitochondrial density let them depend mainly on the far more efficient aerobic respiratory pathway, rather than low-yield anaerobic breakdown.

Muscle fibres are classed as red or white largely on the basis of their myoglobin content — an oxygen-binding, oxygen-storing pigment related to haemoglobin — and how many mitochondria they contain. Red fibres are rich in both: abundant myoglobin keeps a local oxygen supply readily available even during sustained contraction, and a high density of mitochondria provides the machinery needed to run aerobic respiration continuously.

The amount of ATP a working muscle fibre can generate, and how long it can keep generating it without fatigue, depends heavily on which respiratory route it relies on. Aerobic respiration, in which pyruvic acid is completely oxidised via the citric acid cycle and the electron transport system, yields a much larger amount of ATP per glucose molecule than fermentation-type anaerobic breakdown, which produces only a net gain of two ATP per glucose and leaves most of the substrate's energy locked in lactic acid.

Note

White fibres, by contrast, have comparatively little myoglobin and fewer mitochondria, so they depend more heavily on anaerobic glycolysis for quick, powerful bursts of contraction — this produces lactic acid via lactate dehydrogenase, and the build-up of this acid is a major factor in the rapid fatigue seen in intense, short efforts. …

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