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NCERT Exemplar · Q12

Q.Match the following and choose the correct options. Column I: A. Trophoblast, B. Cleavage, C. Inner cell mass, D. Implantation. Column II: i. Embedding of blastocyst in the endometrium, ii. Group of cells that would differentiate as embryo, iii. Outer layer of blastocyst attached to the endometrium, iv. Mitotic division of zygote

(a) A-ii, B-i, C-iii, D-iv
(b) A-iii, B-iv, C-ii, D-i
(c) A-iii, B-i, C-ii, D-iv
(d) A-ii, B-iv, C-iii, D-i
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The trophoblast is the outer layer of the blastocyst that attaches to the endometrium, cleavage is the mitotic division of the zygote, the inner cell mass forms the embryo proper, and implantation is the embedding of the blastocyst in the uterine wall.

After fertilization, the zygote begins a remarkable journey down the fallopian tube toward the uterus, undergoing a series of transformations that prepare it for implantation and subsequent development. Understanding the terminology of early embryonic development is essential to grasp how a single-celled zygote becomes a complex, multi-layered structure capable of establishing pregnancy.

Cleavage is the first major event. The zygote doesn't simply grow larger; instead, it undergoes repeated mitotic divisions without increasing in overall size. Each division produces smaller cells called blastomeres. This process is called cleavage because the original volume is essentially "cleaved" into progressively smaller compartments. By the time the developing embryo reaches the 8–16 cell stage, it resembles a compact ball called a morula.

As cleavage continues, the morula transforms into a blastocyst, a hollow sphere with a fluid-filled cavity. This structure has two distinct components. The outer layer of cells forms the trophoblast, which will not become part of the embryo itself but will instead give rise to the placenta and other supporting membranes. The trophoblast is the interface between the developing embryo and the mother's uterine tissue—it's what attaches to and eventually burrows into the endometrium.

Nestled inside the blastocyst, off to one side, is a cluster of cells called the inner cell mass. This group is the true progenitor of the embryo. While the trophoblast handles attachment and nutrition, the inner cell mass differentiates into all the tissues and organs of the developing baby.

Important

The trophoblast forms the fetal portion of the placenta and secretes enzymes that help the blastocyst embed itself, while the inner cell mass alone gives rise to the embryo proper. …

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