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Polygenic Inheritance · Q23

Q.How does the pattern of phenotypic variation produced by polygenic inheritance differ from that produced by a simple Mendelian (monogenic) trait such as pea flower colour?

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Step 1. A Mendelian (monogenic) trait, such as pea flower colour, is controlled by a single gene with a clear dominant-recessive relationship, producing only a small, fixed number of sharply distinguishable phenotypic classes (e.g. violet or white, with nothing in between).

Step 2. A polygenic trait is instead controlled by the combined, additive contribution of several different genes, none of which individually dominates the outcome.

Step 3. Because these several genes' effects simply add together rather than one masking another, polygenic traits show smooth, continuous variation across a range, with most individuals near the middle and progressively fewer towards either extreme (a bell-shaped distribution). …

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