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Question 45 of 70

Q.Name the chemical alarm signals released by damaged mast cells.

Puducherry TnboardTamil Nadu HSC (DGE) Board 2019Subjective· 3mImportance★★★★★
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Mast cells release histamine, serotonin and bradykinin as chemical alarm signals when damaged or triggered by an allergen.

When an allergen cross-links IgE antibodies bound to a mast cell's surface, the cell degranulates and releases a set of chemical mediators, chiefly histamine (which increases vascular permeability and causes itching/swelling), along with serotonin and bradykinin, which contribute to the inflammatory response by dilating blood vessels and stimulating pain receptors — together producing the classic allergy symptoms (redness, swelling, itching). This rapid …

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