Question 65 of 70
Q.Which antibody characterizes the allergic reaction?
(a) IgM
(b) IgG
(c) IgE
(d) IgA
Puducherry TnboardTamil Nadu HSC (DGE) Board 2018MCQ· 1mImportance★★★★★
93% · 65/70 Questions
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Start your 14-day free trial to unlock the full solution →IgE is the antibody that mediates allergy (Type-I hypersensitivity).
The five human immunoglobulin classes have distinct roles. IgE is present in very low amounts in serum but binds tightly to receptors on mast cells and basophils. When an allergen cross-links this bound IgE on re-exposure, the cells degranulate and release histamine and other mediators, causing the classic allergic symptoms (itching, swelling, bronchoconstriction).
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