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Q.State from where do the signals for parturition originate in human females.

CBSECBSE Class XII Board 2019Subjective· 1mImportance★★★★★
✓ Free question

The signals for parturition (childbirth) originate from the fully developed foetus and the placenta together, which trigger a hormonal cascade ending in childbirth.

In human females, the process of parturition — the act of giving birth — is not a sudden, random event. It is a precisely timed physiological event, and the initiating signals come jointly from the fully developed foetus and the placenta. By the end of pregnancy the foetus is mature, and the placenta itself begins to shift its own hormone output.

Specifically, the placenta reduces its secretion of progesterone — the hormone that had been keeping the uterine muscle relaxed and quiet throughout pregnancy — and increases its secretion of oestrogens.

Note

Progesterone is often called the "pregnancy-maintaining hormone" because it inhibits uterine contractions. A drop in its level is essential for labour to begin.

The rising oestrogen levels have two critical effects. First, they make the uterine muscle (myometrium) more sensitive to oxytocin, a powerful hormone that stimulates contractions. Second, oestrogen stimulates the placenta and foetal membranes to produce prostaglandins, which further help ripen the cervix and strengthen the mild initial uterine contractions — together these mild contractions constitute what is called the foetal ejection reflex.

This mild contraction triggers a reflex — the neuroendocrine reflex — that signals the mother's posterior pituitary gland to release a surge of oxytocin into her bloodstream. This oxytocin then acts on the uterus, causing stronger and more frequent contractions. These stronger contractions push the foetus further, stretching the cervix more, which in turn signals for even more oxytocin release.

Important

This self-amplifying cycle — uterine contraction → cervical stretch → oxytocin release → stronger contraction — is called a positive feedback loop. It is the driving force that continues until the baby is delivered.

So, the initiating signals for parturition come jointly from the fully developed foetus and the placenta, which together set off this hormonal cascade; the mother's body then provides the machinery (oxytocin-driven contractions) for the final delivery.

✓Final answer

The signals for parturition originate from the fully developed foetus and the placenta together. These trigger mild uterine contractions (the foetal ejection reflex) via a shift in the placenta's oestrogen-to-progesterone output and prostaglandin release, which stimulate oxytocin release from the mother's pituitary, setting up a positive feedback loop of stronger contractions that continues until delivery.

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