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Read the following passage and answer the questions that follow. The most convincing evidence to trace evolutionary relationships between humans and different groups of animals come from the basic similarities seen at the molecular level. Study the table given below that depicts the number of amino acid differences between the haemoglobin polypeptide of few animals with that of humans and answer the questions that follow.

S.No.AnimalNo. of amino acid differences in haemoglobin with that of humans
1.Macaque08
2.Dog32
3.Bird45
4.Frog67
5.Lamprey125

(a) To which category of evolution (Divergent or Convergent) do the following evolutionary relationships belong to : (i) Humans and Macaque (ii) Humans and Frog (b) What do the biochemical similarities in haemoglobin suggest about the evolutionary relationship between humans, frog and lamprey ? (c) (i) Which one of the two – lampreys' or macaques' evolution is more closely related to humans and why ? OR (c) (ii) Which one of the two – frogs' or dogs' evolution is more closely related to humans and why ?

CBSECBSE Class XII Board 2025Subjective· 4mImportance★★★★★
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Part (a): both human–macaque and human–frog relationships are divergent evolution; haemoglobin similarity shows human, frog and lamprey share a common ancestor (lamprey diverged earliest); the macaque (8 differences) is far more closely related to humans than the lamprey (125).

Part (c): the dog (32 differences) is more closely related to humans than the frog (67).

Homologous proteins such as haemoglobin serve as molecular evidence of evolution: mutations accumulate over time, so the fewer the amino-acid differences between two species' haemoglobin, the more recently they shared a common ancestor.

Part (a)

(a) Divergent or convergent. The presence of the same homologous protein, haemoglobin, in all these animals is the hallmark of divergent evolution — descent from a common ancestor with subsequent accumulation of differences.

  • (i) Humans and Macaque: divergent (only 8 differences → very recent common ancestor).
  • (ii) Humans and Frog: divergent (67 differences → a much older common ancestor, but still shared). Convergent evolution would require the protein to have arisen independently, which is not the case for such a conserved molecule.

(b) Human, frog and lamprey. The biochemical similarity of haemoglobin in all three means they possess a common evolutionary ancestor from which the protein was inherited. The differences date their splits: human–frog = 67, human–lamprey = 125. Thus the lamprey lineage separated from the human line earliest (most differences), the frog later, so relatedness to humans decreases in the order human → frog → lamprey. …

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