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Q.(a) Explain what is meant by the term amniocentesis. How is this technique misused in India ?

(OR)
(b) Name any two VDs which might occur in a human female. State any two complications in a female if it is left untreated.
CBSECBSE Class XII Board 2025Subjective· 2mImportance★★★★★
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Part (a): amniocentesis = withdrawing amniotic fluid to diagnose foetal genetic disorders; misused in India for illegal sex determination and female foeticide. Part (b): two female VDs are gonorrhoea and syphilis; untreated they cause PID and infertility.

Part (a)

What amniocentesis is. Amniocentesis is a prenatal diagnostic procedure performed usually between the 14th-16th week of pregnancy. A fine needle is inserted through the mother's abdominal and uterine wall into the amniotic sac and a small volume of amniotic fluid is withdrawn. This fluid carries sloughed-off foetal cells and dissolved chemicals. Culturing and analysing these cells allows the karyotype (chromosome number and structure) and various metabolic markers to be studied, so disorders such as Down's syndrome, haemophilia, sickle-cell anaemia and certain enzyme deficiencies can be detected before birth. Used properly it is a valuable tool that lets parents and doctors prepare for a genetic condition.

How it is misused in India. The same chromosomal analysis that detects abnormalities also reveals the sex chromosomes (XX or XY), i.e. whether the foetus is female or male. In a society with a strong preference for a male child, this has been exploited to determine the sex of the foetus and then abort it if it is female. This female foeticide has produced a dangerously skewed child sex ratio in several states. …

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