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Exercise · Q36

Q.If double stranded DNA has 14% C (cytosine) what is percentage of A (adenine), T (thymine) and G (guanine) would you expect?

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Step 1. In double-stranded DNA, Chargaff's rule states that guanine always pairs with cytosine, so the amount of G equals the amount of C: given C = 14%, therefore G = 14% as well.

Step 2. The four bases together must add up to 100%: A + T + G + C = 100%.

Step 3. Since G + C = 14% + 14% = 28%, the remaining percentage must be shared between A and T: A + T = 100% − 28% = 72%. …

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