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Question 44 of 64

Q.If Henle's Loop are absent in mammalian nephron, which one of the following is to be expected?

(a) There will be no urine formation.
(b) There will be hardly any change in the quality and quantity of urine formed.
(c) The urine will be more concentrated.
(d) The urine will be more dilute.
Puducherry TnboardTamil Nadu HSC First Year (DGE) Board 2020MCQ· 1mImportance★★★★★
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The loop of Henle, via the countercurrent multiplier mechanism, sets up a high osmotic gradient in the medulla that lets the collecting duct reabsorb extra water and concentrate urine; without it, urine stays dilute — option (d).

The nephron filters blood in the glomerulus and then selectively reabsorbs water and solutes as the filtrate passes through the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule, and the collecting duct. The loop of Henle, together with the vasa recta, works as a countercurrent multiplier: active transport of NaCl out of the ascending limb (which is impermeable to water) builds up a very high salt concentration deep in the medullary interstitium, while the descending limb (permeable to water) loses water into this concentrated interstitium. This creates a strong osmotic gradient in the medulla.

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