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Question 48 of 56

Q.When the potential across the axon membrane is more negative than the normal resting potential, the neuron is said to be in a state of:

(a) Repolarization
(b) Depolarization
(c) Hypopolarization
(d) Hyperpolarization
Tamil Nadu DgeTamil Nadu HSC First Year (DGE) Board 2025MCQ· 1mImportance★★★★★
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When the membrane potential becomes MORE negative than the normal resting potential, that state is called hyperpolarization.

A neuron at rest maintains a resting membrane potential of about -70 mV (inside negative relative to outside), maintained mainly by the Na+/K+ pump and differential ion permeability. Changes to this potential are named based on their direction:

  • Depolarization: the membrane potential becomes LESS negative (moves toward zero or positive), typically due to Na+ influx — this is the basis of an action potential.
  • Repolarization: after depolarization, the potential returns back toward the resting value, typically due to K+ efflux. …

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