Q.How will you prevent erythroblastosis foetalis ?

Erythroblastosis foetalis is prevented by giving the Rh-negative mother anti-Rh(D) immunoglobulin soon after delivery/exposure so she never develops her own anti-Rh antibodies.

Erythroblastosis foetalis occurs when an Rh-negative mother carries an Rh-positive fetus; during delivery (or events like miscarriage, abortion, or amniocentesis) fetal Rh-positive red blood cells can leak into the mother's bloodstream, causing her immune system to produce anti-Rh antibodies. In a subsequent pregnancy with another Rh-positive fetus, these maternal IgG anti-Rh antibodies can cross the placenta and destroy fetal red blood cells, causing severe haemolytic anaemia in the fetus/newborn. This is prevented by administering an injection of anti-Rh(D) immunoglobulin (commonly known as RhoGAM) to the Rh-negative mother within about 72 hours after delivery of an Rh-positive baby, or after any procedure/event with a risk of fetomaternal blood mixing. These injected antibodies bind to and clear the fetal Rh-positive cells f …