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Question 68 of 73

Q.What is inhibin ?

Puducherry TnboardTamil Nadu HSC (DGE) Board 2026Subjective· 2mImportance★★★★★
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Inhibin is a Sertoli-cell (or granulosa-cell) hormone that feeds back on the pituitary to keep FSH secretion in check, helping regulate the pace of gametogenesis.

In males, the Sertoli cells lining the seminiferous tubules of the testis, besides nourishing developing sperm, secrete the hormone inhibin. Rising levels of inhibin signal to the hypothalamus and anterior pituitary that spermatogenesis is proceeding adequately, and inhibin then suppresses further secretion of Follicle Stimulating Hormone (FSH) through a negative feedback loop, preventing excessive stimulation of the testis. An analogous hormone, also called inhibin, is secreted by the granulosa cells of the growing ovarian follicle in females and similarly provides negative feedback on FSH secretion as part of regulati …

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