Biology · Class 12 Science
Ch 7Human Health and Diseases — Class 12 Biology, concept-first.
Health is far more than simply "not being sick" — the World Health Organization defines it as a state of complete physical, mental, and social well-being. Maintaining that state, in a world full of bacteria, viruses, fungi, and parasites, is the job of the immune system, and immunology is the branch of biology devoted…
Key concepts
Hover a concept to preview it and jump to its most relevant Q&A.
Antigen and Antibody
An antigen is any substance — typically a protein or polysaccharide on a pathogen's surface, or a toxin — that the immune system recognises as foreign and capable of triggering a response.
Most relevant Q&A
- Define an antigen, giving one example of a substance that can act as an antigen.Free
- What is an antibody? Name the class of proteins to which antibodies belong.Free
- With the help of a suitable example, explain what happens during an antigen-antibody reaction.Free
- Describe the structure of an ideal antibody molecule with diagram.Preview
- i) What is the basic difference between agglutination and precipitation of antigen-antibody reaction? ii) Name the causative agent of Filari…Preview
Chapter contents
The NCERT structure, section by section. Open a section to see its questions, then read the concept-first solution.
Basic Concepts of Immunology: Antigen and Antibody
Health is far more than simply "not being sick" — the World Health Organization defines it as a state of complete physical, mental, and social well-being.
Innate Immunity
Innate immunity is the body's built-in, non-specific system of defence. It is called "innate" because a person is born with it, and unlike acquired immunity it does not need any prior contact with a p…
Acquired (Adaptive) Immunity
Where innate immunity treats every threat in roughly the same way, acquired immunity (also called adaptive or specific immunity) is tailor-made for each individual pathogen the body meets, and — most…
Antigen-Antibody Reaction
An antigen-antibody reaction is what happens the moment a matching antibody finds its target antigen. Because each antibody's binding site has a shape that complements one particular epitope on an ant…
Types of Immunity: Active and Passive
Depending on how the antibodies protecting a person actually came to be present in their body, immunity is classified into two broad kinds: active immunity and passive immunity.
Vaccines and Vaccination
Vaccination puts the immune system's memory (section 7.3) to work before a person is ever exposed to a real, disease-causing pathogen.
Parasitic Diseases: Malaria, Filariasis, Ascariasis, and Amoebiasis
A large share of the disease burden covered in the WBCHSE syllabus for this chapter comes from parasites — organisms, either single-celled protozoans or multicellular worms, that live in or on a human…
Arboviral Diseases: Dengue and Chikungunya
Dengue and chikungunya are grouped together in this section because they share the same vector — the day-biting Aedes aegypti mosquito — even though they are caused by two entirely different viruses a…
Bacterial Diseases: Typhoid and Pneumonia
Typhoid and pneumonia are two important human diseases caused by bacteria, but they differ sharply in how they spread and which part of the body they primarily affect.
Viral Diseases: Common Cold and SARS (COVID-19)
This section covers two viral diseases of the respiratory tract that differ enormously in severity — the everyday common cold, and SARS (COVID-19), a disease that became a defining global health event…
Fungal Disease: Ringworm
Ringworm is one of the most common skin infections encountered in a hot, humid climate such as that of West Bengal, and despite its name, it has nothing to do with any worm at all — it is a fungal inf…
Allergy
An allergy is what happens when the immune system responds to a substance that is, for most people, entirely harmless, as though it were a dangerous invader.
Autoimmune Disorders
The immune system normally relies on a careful ability to distinguish the body's own cells and molecules ("self") from anything foreign ("non-self"), attacking only the latter.
Cancer
Cancer is not one single disease but a large group of diseases that share one defining feature: the uncontrolled and abnormal division of cells.
HIV and AIDS
HIV, the Human Immunodeficiency Virus, is a retrovirus — meaning its genetic material is RNA rather than DNA, and it carries a special enzyme, reverse transcriptase, that lets it convert its RNA into…
Adolescence: Drug and Alcohol Abuse
Adolescence, roughly the second decade of life, is a period of rapid physical growth, emotional development, and social change, as a young person moves from childhood towards adulthood.
Summary
This chapter surveyed how the human body defends itself and the major diseases named in the WBCHSE syllabus for Chapter 7.
Very Short Answer Questions
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- Q1Define an antigen, giving one example of a substance that can act as an antigen.Free
- Q2What is an antibody? Name the class of proteins to which antibodies belong.Free
- Q3Name the protozoan parasite that causes malaria in humans.Free
- Q4Name the common mosquito vector responsible for transmitting both dengue and chikungunya.Preview
- Q5Expand the abbreviation AIDS.Preview
- Q6Define an allergen and give one common example.Preview
- Q7Name the bacterium that causes typhoid fever.Preview
- Q8What is meant by 'herd immunity'?Preview
- Q9Name the virus responsible for most cases of the common cold.Preview
- Q10Define vaccination in one or two sentences.Preview
Short Answer Questions
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- Q11Distinguish between innate immunity and acquired immunity on the basis of specificity and memory.Free
- Q12With the help of a suitable example, explain what happens during an antigen-antibody reaction.Free
- Q13Differentiate between active immunity and passive immunity, giving one example of each.Free
- Q14Why does the secondary immune response occur faster and stronger than the primary immune response?Preview
- Q15Name the stage of the life cycle of Plasmodium that is directly responsible for the recurring bouts of fever and chill in a malaria patient,…Preview
- Q16How does filariasis spread from person to person, and what are its characteristic symptoms?Preview
- Q17Name the causative organism of ascariasis and describe how a person typically becomes infected.Preview
- Q18Describe the mode of transmission of amoebiasis and state one important preventive measure against it.Preview
- Q19List two symptoms and two preventive measures for typhoid fever.Preview
- Q20How would you distinguish pneumonia from the common cold on the basis of their causative agents and the part of the respiratory system prima…Preview
- Q21Explain how ringworm spreads from one person to another, and suggest two ways to prevent it.Preview
- Q22What is an autoimmune disorder? Name one autoimmune disorder that affects the joints.Preview
- Q23List any three modes by which HIV can spread from an infected person to a healthy person.Preview
- Q24Mention any three harmful physical or psychological effects of long-term drug or alcohol abuse.Preview
- Q25Why are adolescents particularly vulnerable to drug and alcohol abuse? Suggest two preventive measures.Preview
Long Answer Questions
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- Q26Describe the different types of cells and organs involved in the human immune system, and explain how innate immunity and acquired immunity…Free
- Q27Discuss, with examples, the different types of immunity a human being can acquire, covering active, passive, natural, and artificial immunit…Free
- Q28Describe the life cycle of the malarial parasite Plasmodium in the human body and in the female Anopheles mosquito, and explain how this cyc…Free
- Q29Compare malaria, dengue, and typhoid fever under the heads: causative agent, mode of transmission, symptoms, and prevention.Preview
- Q30Describe the main differences between a normal cell and a cancer cell, and explain the common methods used to detect and diagnose cancer.Preview
- Q31Describe the structure of the Human Immunodeficiency Virus (HIV) and explain, step by step, how it replicates inside a helper T-lymphocyte t…Preview
- Q32Explain the mechanism by which an allergic reaction occurs in the body, and describe what goes wrong in an autoimmune disorder, using rheuma…Preview
- Q33Discuss the problem of drug and alcohol abuse among adolescents — its common causes, its physical and social effects, and the preventive mea…Preview
Sample & Board Papers
Sample papers and previous-year board questions for this subject.
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- Q1Write down the full forms of HIV and AIDS. **OR** What do you mean by vaccination?Preview
- Q2Write down the scientific name of causal organism of each of the following diseases: Ascariasis, Typhoid, Ringworm. **OR** Mention the mode…Preview
- Q3What is carcinogen? How can you prevent the occurrence of cancer? **OR** Draw and describe the structure of a typical antibody.Preview
- Q4Active immunization can be brought about by (a) vaccination (b) injecting specific antibodies (c) injecting many allergens (d) none of these…Preview
- Q5Mention the scientific name of the microbe responsible for gonorrhea. **OR** What is the full form of ZIFT?Preview
- Q6Which one of the following antibodies present in breast milk of humans protect the newborn baby from infections? (a) Ig A (b) Ig D (c) Ig E…Preview
- Q7Plasma cell is related to which type of immunity? (a) Cell mediated immunity (b) Humoral immunity (c) Innate immunity (d) None of thesePreview
- Q8Polio vaccine is prepared by which one of the following processes? (a) Attenuated virus (b) Dead pathogen (c) Surface chemical (d) ToxoidPreview
- Q9Differentiate between temporary and permanent parasites.Preview
- Q10What is the full form of LSD? Which type of drug is this? (1+1) **OR** What do you mean by mixed composite fish culture?Preview
- Q11Mention the mode of transmission in amoebiasis. What is the reason of AIDS? (2+1) **OR** Mention in brief the process of hypophysation. Writ…Preview
- Q12Generally anthrax disease affects (a) Cattles (b) Fishes (c) Poultry birds (d) HoneybeePreview
- Q13Which one of the following is not responsible for Innate Immunity? (a) Spleen (b) HCl in stomach (c) Skin (d) T-lymphocytePreview
- Q14Give the scientific name of the protozoa which causes Malignant Malaria disease.Preview
- Q15Distinguish between Cellular and Humoral Immunity. Mention the scientific name of the parasite responsible for the Benign Tertian Malaria. (…Preview
- Q16Mention a few ill effects of alcohol consumption in human. Which kind of drug is cocaine? (2+1)Preview
- Q17BCG is a vaccine against (a) Typhoid (b) Tuberculosis (c) Measles (d) Chicken poxPreview
- Q18Both B-cells and T-cells of immune system are produced in (a) Spleen (b) Lymphoid nodes (c) Bone marrow (d) ThymusPreview
- Q19What is incubation period in case of a disease?Preview
- Q20State the differences between innate immunity and adaptive immunity.Preview
- Q21Name the virus responsible for causing AIDS. Diagrammatically describe the structure of this virus. (1+2) **OR** What is vaccination? How ca…Preview
- Q22Write down the scientific name of each causal organism of each of the following diseases: Filariasis, Pneumonia, Ascariasis. **OR** Describe…Preview
- Q23Describe in brief the process of transmission of Malaria disease.Preview
- Q24What do you mean by Vaccination? Mention in brief the cause and symptoms of Typhoid.Preview
- Q25What is Carcinogen? How can you prevent the occurrence of Cancer?Preview
- Q26State two effects of β-alcoholism in human body.Preview
- Q27Give an example of each type : i) life attenuated vaccine ii) toxoid vaccine iii) inactivated vaccine iv) recombinant vaccinePreview
- Q28Describe the structure of an ideal antibody molecule with diagram.Preview
- Q29i) What is the basic difference between agglutination and precipitation of antigen-antibody reaction? ii) Name the causative agent of Filari…Preview
More questions
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- Q34Which type of lymphocyte, upon re-exposure to the same antigen, mounts a rapid secondary immune response because of immunological memory? (A…Free
- Q35The common mosquito vector responsible for transmitting both dengue and chikungunya viruses is: (A) Anopheles mosquito (B) Culex mosquito (C…Free
- Q36Which of the following diseases is caused by a protozoan parasite? (A) Ascariasis (B) Amoebiasis (C) Ringworm (D) TyphoidFree
- Q37HIV stands for: (A) Human Infectious Virus (B) Human Immunodeficiency Virus (C) Human Influenza Virus (D) Human Inflammatory VirusPreview
- Q38Passive immunity is best described as immunity that is: (A) Developed by the body's own immune system after natural infection (B) Provided b…Preview
- Q39Ringworm, a common skin infection seen in hot, humid climates, is caused by a: (A) Bacterium (B) Virus (C) Fungus (D) ProtozoanPreview
- Q40Rheumatoid arthritis, in which the body's own immune system attacks its joint tissue, is an example of a/an: (A) Allergic reaction (B) Autoi…Preview
- Q41SARS-CoV-2, the virus responsible for COVID-19, primarily infects and causes disease mainly in which human system? (A) Digestive system (B)…Preview