Q.The nuclides with odd number of both protons and neutrons are the least stable. Why?
Step 1. Stability from nucleon pairing works WITHIN each type of nucleon separately: protons pair with protons, and neutrons pair with neutrons -- a proton does not pair with a neutron in this sense.
Step 2. In a nuclide with an odd number of protons, one proton is inevitably left without a partner; in a nuclide with an odd number of neutrons, one neutron is likewise left unpaired.
Step 3. A nuclide with BOTH Z and N odd therefore has two separate unpaired nucleons at once -- one lone proton and one lone neutron -- so it misses out on two independent sources of pairing stabilisation, rather than just one.
Step 4. This is reflected directly in the observed count of stable nuclides: only 4 stable odd-Z, odd-N nuclides are known (about 2% of the Earth's crust), far fewer than any of the other three even/odd combinations.
Odd-Z, odd-N nuclides have two separate unpaired nucleons (an unpaired proton and an unpaired neutron, which cannot pair with each other), so they lose the stabilising effect of pairing twice over -- which is why only 4 such stable nuclides exist in nature.
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