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Use your brain power · Q1

Q.Tryptophan and histidine have the structures (I) and (II) respectively. Classify them into neutral/ acidic/basic ∝-amino acids and justify your answer.(Hint : Consider involvement of lone pair in resonance).

Structures I (tryptophan) and II (histidine)
Figure
Maharashtra MsbshseTextbookSubjectiveImportance★★★★★est
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  • Tryptophan (I): its ring nitrogen is a pyrrole-type N-H whose lone pair is delocalized INTO the aromatic indole system — it cannot bind a proton, so the side chain adds no basicity: a neutral amino acid. …

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