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Question 78 of 97

Q.Draw the structure of chromosome and label its parts.

Puducherry TnboardTamil Nadu HSC (DGE) Board 2019Subjective· 3mImportance★★★★★
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Figure — The stem asks to draw and label a chromosome, and the answer needs chromatids, centromere/primary constriction
Figure — The stem asks to draw and label a chromosome, and the answer needs chromatids, centromere/primary constriction

A chromosome's labelled parts are: two chromatids, the centromere/kinetochore, telomeres, and (in SAT-chromosomes) a secondary constriction with a satellite.

Since a diagram cannot be rendered here, the structure of a typical (metaphase) chromosome is described part by part, as it would be labelled:

  • Chromatid: each chromosome at metaphase consists of two identical sister chromatids (formed by replication of the DNA during S-phase), lying side by side and joined together at one point.
  • Centromere (primary constriction): the narrow, constricted region where the two sister chromatids are held together; its position (median, sub-median, sub-terminal or terminal) determines the chromosome's shape (metacentric, sub-metacentric, acrocentric or telocentric).
  • Kinetochore: a disc-shaped protein structure present on the centromere, to which the spindle fibres (microtubules) attach during cell division, enabling the chromatids to be pulled to opposite poles.
  • Chromonemata: the coiled thread-like structures within each chromatid that carry the genes, embedded in a matrix.
  • Telomere: the specialised, physically and chemically distinct terminal region at each end of the chromatid; it caps and stabilises the chromosome end, preventing it from fraying, fusing with other chromosomes, or being recognised as damaged DNA. …

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