Q.Which event is represented by the diagram given below, related to chromosomal aberrations? (see figure)
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Start your 14-day free trial to unlock the full solution →(c) Inversion — the segment B-C-D has been reversed in order to D-C-B.
A chromosomal segment whose gene order is reversed (but genes retained) illustrates inversion.
Comparing the two gene sequences shown — A B C D E F G H changing to A D C B E F G H — the same genes B, C and D are still present in the chromosome, but their internal order has been reversed (B-C-D became D-C-B), with the rest of the sequence (A, E, F, G, H) unchanged. This is the defining signature of an inversion, in which a chromosomal segment breaks at two points, flips end-to-end (rotates 180°), and rejoins, reversing the gene order within that segment. Deletion would r …
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