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Question 48 of 80

Q.Abortion in the first trimester of pregnancy may occur due to lack of _______.

(a) aldosterone
(b) testosterone
(c) oestrogen
(d) progesterone
Maharashtra MsbshseMaharashtra HSC (MSBSHSE) Board 2017MCQ· 1mImportance★★★★★
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Correct answer: (d) progesterone

Progesterone maintains the uterine lining in early pregnancy; its deficiency can lead to loss of that lining and abortion.

Progesterone, secreted initially by the corpus luteum and later by the placenta, is essential for maintaining the endometrium (uterine lining) in a thickened, vascularised, secretory state suitable for implantation and continued support of the developing embryo, and it also suppresses uterine contractions and further ovulation during pregnancy. If progesterone levels are insufficient during the first trimester, the endometrium cannot be adequately maintained, which can result in its breakdown and consequent abortion/miscarriage. Aldosterone regulates sodium/water bal …

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