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Q.Give reason: When Rh –ve mother conceives Rh +ve foetus, then she is given injection of anti Rh antibodies.

Maharashtra MsbshseMaharashtra HSC (MSBSHSE) Board 2025Subjective· 2mImportance★★★★★
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The anti-Rh (Anti-D) injection prevents the Rh-negative mother's immune system from forming her own antibodies against the Rh antigen of the foetus's blood, thereby protecting a future Rh-positive pregnancy from haemo...

Anti-D injection stops the mother's immune system from making anti-Rh antibodies that would harm a future Rh+ baby.

When an Rh-negative mother carries an Rh-positive foetus, foetal Rh-positive red blood cells can enter the maternal circulation (usually at delivery), triggering the mother's immune system to produce anti-Rh antibodies. These maternal antibodies pose no threat to the current pregnancy (sensitisation happens too late), but in a subsequent Rh-positive pregnancy they can cross the placenta and destroy the foetal red blood cells, causing severe haemolytic anaemia/erythroblastosis foetalis. To prevent this, an injection of ready-made anti-Rh (Anti-D) antibodies is given to the mother soon after each del …

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