Q.Explain blood clotting in short.
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Start your 14-day free trial to unlock the full solution →Blood clotting converts liquid blood into a solid mass through a clotting-factor cascade that ends with fibrin trapping blood cells.
Blood clotting (coagulation) is triggered either by blood touching a foreign surface (the intrinsic pathway) or by contact with damaged tissue (the extrinsic pathway, via released tissue thromboplastin). Both pathways run through a step-wise cascade of clotting factors and converge on activating clotting factor X. Thromboplastin also helps form the enzyme prothrombinase, which converts the inactive plasma protein prothrombin into the active enzyme thrombin (and inactivates heparin, the natural anticoagulant, along the way). Thrombin then converts the soluble plasma protein fibrinogen into insoluble fibrin, which forms a …
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